Stereochemistry Of Organic Compounds Eliel Pdf Free 291 [VERIFIED]
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Stereochemistry of Organic Compounds by Ernest L. Eliel: A Comprehensive Review
Stereochemistry is the study of molecules in three dimensions, and how their spatial arrangements affect their properties and reactions. Stereochemistry is an essential topic for organic chemistry, as it determines the selectivity, specificity, and mechanism of many organic transformations. Stereochemistry also plays a key role in biological processes, such as enzyme catalysis, drug action, and molecular recognition.
One of the most authoritative and comprehensive books on stereochemistry is Stereochemistry of Organic Compounds by Ernest L. Eliel and Samuel H. Wilen, published by John Wiley & Sons in 1994[^1^]. This book is a revised and updated edition of Eliel's classic work Stereochemistry of Carbon Compounds, which was first published in 1962 and became a landmark in the field. The book covers all aspects of modern stereochemistry, including:
Asymmetric and diastereoselective synthesis
Conformational analysis
Properties of enantiomers and racemates
Separation and analysis of enantiomers and diastereoisomers
Developments in spectroscopy (including NMR), chromatography, and molecular mechanics as applied to stereochemistry
Prostereoisomerism
Conceptual foundations of stereochemistry, including terminology and symmetry concepts
Chiroptical properties
The book contains more than 4,000 references, 1,000 illustrations, and a glossary of stereochemical terms. It is written in a clear and rigorous style, with numerous examples and exercises to illustrate the concepts and applications. The book is suitable for advanced undergraduate and graduate students, as well as researchers and practitioners in organic chemistry, biochemistry, medicinal chemistry, pharmacology, and related fields.
A PDF version of the book can be downloaded for free from various online sources[^2^] [^3^] [^4^]. However, readers are advised to respect the copyright of the authors and publishers, and to use the PDF version only for personal or educational purposes. The PDF version may also have some errors or omissions compared to the original printed version.
Stereochemistry of Organic Compounds by Ernest L. Eliel and Samuel H. Wilen is a classic and indispensable reference for anyone interested in the fascinating world of molecules in 3D.
One of the main challenges in stereochemistry is the synthesis of enantiomerically pure or enriched compounds, which have different biological activities and properties than their mirror images. For example, one enantiomer of a drug may be effective and safe, while the other may be inactive or toxic. Therefore, methods for controlling the stereochemistry of organic reactions are highly desirable and valuable.
Stereochemistry of Organic Compounds provides a comprehensive overview of the methods and strategies for asymmetric and diastereoselective synthesis, such as:
Chiral auxiliaries and reagents
Catalytic asymmetric synthesis
Stereospecific reactions
Chiral pool synthesis
Biocatalysis and enzymatic resolution
Dynamic kinetic resolution
Asymmetric induction and amplification
Stereodivergent synthesis
The book also discusses the principles and applications of conformational analysis, which is the study of the preferred shapes and orientations of molecules in space. Conformational analysis is important for understanding the stereochemical outcome and mechanism of reactions, as well as the physical and biological properties of molecules. The book covers topics such as:
Conformational energy and potential energy surfaces
Conformational equilibria and kinetics
Steric effects and strain
Torsional effects and coupling constants
Conformational analysis of cyclic and acyclic compounds
Conformational analysis of peptides, carbohydrates, and nucleic acids
Molecular modeling and simulation 061ffe29dd